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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LRCH4
All Species:
13.64
Human Site:
S222
Identified Species:
42.86
UniProt:
O75427
Number Species:
7
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75427
NP_002310.2
683
73450
S222
R
V
S
R
I
P
V
S
F
C
R
L
R
H
L
Chimpanzee
Pan troglodytes
XP_001167143
779
86714
C236
K
I
T
T
I
P
V
C
Y
R
N
L
R
H
L
Rhesus Macaque
Macaca mulatta
XP_001086884
683
73602
S222
R
V
S
R
I
P
V
S
F
C
R
L
R
H
L
Dog
Lupus familis
XP_546954
669
71773
S222
R
V
S
R
I
P
V
S
F
C
R
L
R
H
L
Cat
Felis silvestris
Mouse
Mus musculus
Q921G6
680
73145
S222
R
I
S
R
I
P
V
S
F
C
R
L
R
H
L
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514226
691
77204
C218
K
V
L
A
I
P
I
C
F
R
G
M
K
Q
L
Chicken
Gallus gallus
Q5ZLN0
603
67457
L158
S
H
L
K
G
L
L
L
Q
H
N
E
L
S
H
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q22875
559
62465
E114
K
L
T
C
L
P
T
E
I
G
Q
L
V
N
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
42.8
97
79.8
N.A.
85.3
N.A.
N.A.
40.5
22.1
N.A.
N.A.
N.A.
N.A.
N.A.
20
N.A.
Protein Similarity:
100
57.6
97.9
84.1
N.A.
91.6
N.A.
N.A.
54.2
39.6
N.A.
N.A.
N.A.
N.A.
N.A.
36.7
N.A.
P-Site Identity:
100
46.6
100
100
N.A.
93.3
N.A.
N.A.
33.3
0
N.A.
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
100
73.3
100
100
N.A.
100
N.A.
N.A.
60
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
60
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
13
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
13
0
0
0
25
0
50
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
13
0
0
0
13
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
63
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
13
0
0
0
0
13
13
0
0
0
0
% G
% His:
0
13
0
0
0
0
0
0
0
13
0
0
0
63
13
% H
% Ile:
0
25
0
0
75
0
13
0
13
0
0
0
0
0
0
% I
% Lys:
38
0
0
13
0
0
0
0
0
0
0
0
13
0
0
% K
% Leu:
0
13
25
0
13
13
13
13
0
0
0
75
13
0
88
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
13
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
25
0
0
13
0
% N
% Pro:
0
0
0
0
0
88
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
13
0
13
0
0
13
0
% Q
% Arg:
50
0
0
50
0
0
0
0
0
25
50
0
63
0
0
% R
% Ser:
13
0
50
0
0
0
0
50
0
0
0
0
0
13
0
% S
% Thr:
0
0
25
13
0
0
13
0
0
0
0
0
0
0
0
% T
% Val:
0
50
0
0
0
0
63
0
0
0
0
0
13
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
13
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _